Results of off-pump myocardial revascularization in female patients

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Sharipov I. M., Yarbekov R. R., Ismatov A. A., Muradov M. M., Omonov S. K., Vakhidov T. Z.

Republican Specialized Center of Cardiology (Tashkent, Uzbekistan);

On-pump myocardial revascularization operations in female sex patients are considered more risky in connection with anatomo-physiological peculiarities of the latter. Very little is known about the results of off-pump myocardial revascularization operations in this group of patients. AIMS OF THE STUDY. The purpose of the work is to study the results of off-pump myocardial revascularization in female patients. MATERIAL AND METHODS. A comparative analysis of the results of surgical treatment of 350 patients with ischemic heart disease, to whom were performed off-pump myocardial revascularization operations, was done. All patients, depending on their gender, were divided into two groups: group I - 56 (16.0%) female patients, and group II – 294 (84.0%) male patients. The average age of patients in the first group was 61,9±8,0 years, and in group II - 60,1±6,9 years. Patients of both groups were comparable in the presence of concomitant pathology. The study of Morphometric indices revealed a significant difference in average growth (157 cm versus 171 cm), weight (73.3 against 83.5 kg) and body surface area (1.78 m2 versus 1.98 m2). It was also revealed that patients of the group II had larger LV size and volume on Echo. The risk of surgery by EuroScore calculator amounted to 5,1±2.5 points (or 5.4±4.7%) in group I and 3.9±2.4 points in group II (or 3.9±3.7%), the difference was statistically significant (p=0,002). RESULTS AND DISCUSSION. The duration of the operation in both groups amounted to 218,5±52,0 and 231,9±55,5 min respectively. The average blood loss amounted to 501 ml and 502 ml respectively. In the first group, the average number of grafts amounted to 2,92±0.7 per patient (1-4 grafts), while in the second group – 3.2±0.7 grafts (p=0,006). Inotropc support intraoperatively and in the immediate postoperative period was necessary in the first group in 36% of patients, and in II group - in 37.5%. The average time of ventilation in the ICU was in the group I - 6.5±4.3 hours, in II Group - 5.6±3.0 hours (p=0,07). The ICU stay averaged 46,1±19,5 hours in group I and 47,9±21,9 hours in group II. In the first group hospital mortality amounted to 1.8% (1 patient) - at expected 5.4%, and in II Group - 1.0% (3 patients) - with the expected 3,9%. CONCLUSIONS. Off-pump myocardial revascularization operations in female patients are safe and can be performed with low levels of complications and hospital mortality.

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