Blehm A.
UNI Klinik Düsseldorf;
Objectives: Aortic root replacement is a complex procedure, thought subsequent modifications of the original Bentall procedure have made aortic root surgery more reproducible. Due to the high risk patients with a mechanical valve are exposed to using coumarine derivatives , many attempts for a biological solution have been made. We retrospectively examined the outcomes of the modified Bentall procedure, using the new BioSurgical BioIntegral an all-Biologic Xenopericardial Conduit in 171 Patients. Methods: Between May 2015 and May 2018 a total of 171 Patients underwent aortic root replacement using the BioIntegral Conduit. Demographics showed a mean age of 70,98 years, 35% were female and the mean risk profile EuroSCORE-II was 2,59%. A total of 20 patients presented with acute Type-A dissection. Primary study endpoints were hemodynamic performance during follow-up, including mean pressure gradient and effective orifice areas. Secondary study endpoints were postoperative outcome within 30 day and 1-year survival. Results: 30-day mortality was 11%, 1-year mortality was 13%. Complikations was: stroke 8%, bleeding was11%, endokarditis was 1%, AV Block was 6%. Mean Bypass time was 134 minutes , aortic clamp time was 103 minutes and mean reperfusion time was 25 minutes. CONCLUSIONS: The present small single-center study is one of the first to evaluate the Bio Surgical BioIntegral biological aortic-valved conduit in the aortic root position. It shows optimal hemodynamic results.
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