Vasoactive–inotropic score: a predictor of the development of multiple organ dysfunction syndrome in children after extracorporeal circulation

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Ботизату А. И.

ГMФУ им. Николае Тестемицану;

Background. Children who suffer congenital heart surgery with extracorporeal circulation are at high risk of significant postoperative morbidity and mortality. Despite the fact that the score has not yet been established as a predictor of postoperative outcomes, this score was further used in clinical research as a measure of disease severity in patients undergoing surgical correction of the CHD. Objective. To determine the association between vasoactive inotropic score and clinical outcome in children after cardiac surgery. Material and methods. Between June 2010 December 2015 in the intensive care unit were admitted 45 patients undergoing surgical correction in conditions of extracorporeal circulation of Fallot's tetralogy. Results. Were registered all doses of vasoactive preparations in the first 24 hours after surgery and was calculated the vasoactive-inotropic score. Only 27% of patients who have developed MODS had a score <5p, and 33% had a score <10p, but 58% of patients had a score <15p and 100% of patients who have developed MODS had a score >15p. Also scoring high inotropic-vasoactive was associated with prolonged ICU stay and duration of mechanical ventilation increased. Also a higher vasoactive inotropic score was associated with prolonged ICU stay and a increased duration of mechanical ventilation. Conclusion. Congenital cardiac surgery with extracorporeal circulation predict the eventual morbidity in young children. The usefulness of vasoactive inotropic score as an independent predictor of the development of MODS in children after cardiac surgery may have important implications for future research.

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