Ботизату А. И.
ГMФУ им. Николае Тестемицану;
Background. Acute kidney injury (AKI) is one of the most common and severe complications in cardiac surgery. Application of the RIFLE classification (risk, injury, failure and end stage renal disease) is validated in pediatric population. Objective. To determine AKI appearance in the patients up to 18 years, using modified RIFLE criteria, validated in children (pRIFLE), the relationship between AKI with other complications after surgical correction in Tetralogy of Fallot. Materials and methods. From the database of the Republican Clinical Hospital, were selected 45 children underwent surgical correction of Tetralogy of Fallot between June 2010 and December 2015. Acute kidney injury was defined as a decrease in estimated creatinine clearance based on the pediatric modified RIFLE (pRIFLE) criteria. Results. Twenty-two patients (48,9%) had AKI by pRIFLE criteria. Acording to pRIFLE, 15 (33.3%) patients corresponded to criteria of ”Risk”; 6 (13.3%) patients corresponded to the criteria of ”Injury” and one (2.2%) patient met criteria for ”Failure”. Three patients (6.7%) died. The occurrence of MODS was encountered in 19 (42.2%) patients, sepsis was met in 3 (6.7%) patients. Duration of mechanical ventilation (p <0.001) and length of stay in the intensive care unit (p <0.001) were significantly higher compared with the group of 23 patients who did not develop signs of acute kidney injury. Conclusions. Acute kidney dysfunction was independently associated with increased occurrence of postoperative complications after surgical correction of Fallot's tetralogy. AKI influenced postoperative mortality.
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